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PhD Position (m/f/d) - Computational Biology & Single-Cell Genomics - Decoding Brain Development

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Universitätsklinikum Carl Gustav Carus Dresden
Munkavégzés helye

Németország

Munkaidő, foglalkoztatás jellege
- Teljes munkaidő
- Általános munkarend
Elvárások
- Angol középfok
- 1-3 év tapasztalat
- Főiskola

Állás elmentve

A hirdetést eltávolítottuk a mentett állásai közül.

Responsibilities

Analysis and interpretation of high-resolution single-cell RNA-seq and scATAC-seq data to elucidate cellular processes
Processing and integration of spatial transcriptomics data to reveal molecular patterns in their tissue context
Development, optimization, and application of bioinformatic pipelines for data integration, analysis, and visualization of complex datasets
Computational modeling of gene regulatory networks to investigate molecular control mechanisms
Active contribution to scientific publications and support in project and third-party funding applications with the aim of completing a doctorate (Ph.D. / Dr. rer. medic.)
Supervision and technical support of students (Bachelor's, Master's, medical students) in daily laboratory and project work

Requirements

Completed university degree in bioinformatics, computational biology, statistics, or a comparable field
Strong programming skills in common analysis environments such as R and/or Python
Experience in the analysis of single-cell genomics data, ideally using tools such as Seurat or Scanpy
Enthusiasm for statistical modeling and machine learning to analyze complex biological datasets
High level of care and attention to detail
Excellent teamwork and communication skills
Initiative and strong self-organization skills

What we offer

at the Institute of Clinical Genetics

The doctoral position is available as soon as possible and is initially limited to a period of three years. Remuneration is based on the pay scale regulations of the Collective Agreement for the Public Service of the Federal States (TV-L) and, subject to personal eligibility, is possible at pay group E13 (65% doctoral position).

Convincing Across the Board:

A stimulating research environment at a leading university medical center
Access to TUD High-performance computing resources
Close supervision and integration into collaborative research networks
Compensation: In accordance with the collective agreement, plus an annual special payment, subject to personal eligibility
Leave: 30 days of paid annual leave
Professional Development: Extensive internal and external training and continuing education opportunities to continuously strengthen your skills
Work Culture: We value transparency, team spirit, and shared success. Join us at social events or sporting activities such as the REWE Team Challenge
Mobility: Job bike program and subsidy for public transport tickets to support an environmentally friendly and convenient commute
Health & Well-being: Access to modern sports and exercise programs at our health center, mental health initiatives, and comprehensive occupational health management
Employee Benefits: Discounts at our hospital pharmacy, exclusive corporate benefits, and additional shopping platforms

Company info

The Functional Neurogenomics research group led by Philipp Abe investigates the molecular foundations of brain development, with a particular focus on the early formation of neuronal circuits. Within the framework of the “ThalamoConnect” project, state-of-the-art single-cell technologies and bioinformatic analyses are employed to decipher the genetic programs that govern the connectivity of brain regions and play a role in neurological disorders when these processes are disrupted.