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Bioinformatician / Computational Biologist (m/f/d)

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Universitätsklinikum Carl Gustav Carus Dresden
Munkavégzés helye

Németország

Munkaidő, foglalkoztatás jellege
- Teljes munkaidő
- Általános munkarend
Elvárt technológiák
- R PYTHON PANDAS GIT
Elvárások
- Angol középfok
- 1-3 év tapasztalat
- Egyetem

Állás elmentve

A hirdetést eltávolítottuk a mentett állásai közül.

Responsibilities

Analysis, integration, and interpretation of high-dimensional omics datasets in translational research
Bioinformatic analysis of:
Bulk RNA sequencing
Single-cell and single-nucleus RNA sequencing
CITE-seq
ATAC-seq
NGS-based datasets
Metabolomics and proteomics data
Development, extension, and maintenance of robust and reproducible analysis pipelines, including quality control, normalization, annotation, and statistical analysis
Multi-omics integration (e.g. transcriptomics, epigenomics, metabolomics, proteomics) to derive biologically and clinically meaningful insights
Close collaboration with experimental scientists, clinicians, and diagnostic partners
Support in the methodological implementation of bioinformatic workflows in translational and, where applicable, clinically oriented settings
Contribution to scientific publications, third-party funding applications, and presentations

Requirements

A completed university degree with a PhD in Bioinformatics, Computational Biology, Systems Biology, Biostatistics, Molecular Medicine, or a related discipline
Proven hands-on experience in the analysis of omics datasets, in particular:
Bulk and single-cell RNA-seq
CITE-seq and/or ATAC-seq
Ideally metabolomics and/or proteomics
Excellent programming skills in R, including experience with relevant Bioconductor frameworks (e.g. Seurat, SingleCellExperiment, edgeR, DESeq2)
Good to very good knowledge of Python (e.g. Scanpy, Pandas, NumPy, SciPy)
Experience in developing, extending, and documenting reproducible analysis pipelines (e.g. using Snakemake, Nextflow, Git)
Solid understanding of statistical methods, data integration strategies, and visualization of complex datasets
A structured, independent working style combined with strong communication and teamwork skills
Strong interest in translational research and the application of bioinformatics methods in a medical context

What we offer

Institute for Clinical Chemistry and Laboratory Medicine, University Hospital Dresden

Participation in highly relevant scientific projects in the area of chronic inflammatory diseases and cancer research
An interdisciplinary environment with close interaction with clinical partners
Modern IT and data analysis infrastructure
Opportunities for scientific career development, including habilitation
Comprehensive occupational health and fitness programs (Carus Vital)
Extensive professional training and development opportunities through the Carus Academy
Occupational pension scheme
Job ticket for public transportation in Dresden and the surrounding area

Company info

The Institute for Clinical Chemistry and Laboratory Medicine at the University Hospital Dresden is seeking to appoint a Bioinformatician / Computational Biologist (m/f/d) at the earliest possible date. The position focuses on the analysis and integration of complex omics datasets and Omics Data Analysis and Multi-Omics Integration in Translational Researchin translational research projects with close links to clinical diagnostics.